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Senior Scientist Chemistry (PhD)

Oss, Netherlands

Are you a passionate Organic/Medicinal Chemist who holds a PhD and has gained additional experience during a post doc or experience within the pharmaceutical industry? To strengthen our Medicinal Chemistry team we are looking for a Senior Scientist Chemistry to help identify novel therapies against haematological cancers.

Acerta Pharma in Oss, the Netherlands, is fully integrated in the AstraZeneca group and dedicated to the discovery and development of novel therapies against haematological malignancies. We have recently moved into our new research facility, the Marie-Curie building in the Pivot Park, with state-of-the-art laboratories in place and operative.

Senior Scientist Chemistry (PhD)
Pivot Park, Oss, Netherlands

Your challenge:
As a Research Scientist Chemistry you will help to build Acerta's haematological oncology portfolio. The projects you will be working on can range across the whole spectrum of small molecule development stages and modalities, from early hit identification to late stage lead optimisation. Acerta’s drug discovery research is fully integrated in the AstraZeneca organisation and there will be multiple interactions with colleagues from AstraZeneca.

With your knowledge and experience in advanced organic chemistry and possibly medicinal chemistry, you will be asked to give your critical contribution to the progress of the projects through key milestones. We will enable you to grow into all aspects of modern medicinal chemistry.

What will you be doing?
•    Based on your experience and skills you will contribute to the design and execution of synthetic routes to drive the optimization of hit/lead series.
•    With creativity and troubleshooting mentality you will effectively help to overcome synthetic difficulties in the laboratory.
•    You will be seeking for opportunities to apply new technologies and ways of working  to increase synthesis efficiency. We have instrumentation in place for advanced organic synthesis like electrochemistry, photochemistry and reactions in flow.
•    You will effectively and concisely present your results in meetings and contribute to fruitful discussions.
•    Take ownership on series of compounds under optimisation and grow over time into in applying AI/Computational Chemistry supported Medicinal Chemistry design principles.

What do you bring?
•    You have completed a Master study program in Chemistry, (bio)Pharmaceutical Sciences, or related, followed by a PhD (must have) in Organic/Medicinal Chemistry.
•    Working experience in the pharmaceutical industry and/or a post doc in Organic or Medicinal Chemistry is highly desirable but not a must have.
•    Excellent team-working skills.
•    Scientific publications in peer-reviewed chemistry-related journals are desirable.
•    You are fluent in English and willing to relocate to the Oss area if needed.

What do we offer
•  A dynamic, innovative, growing and international working environment in a global science-driven organisation with a leading role in developing novel treatments for Haematological malignancies.
• The opportunity to work in a vibrant, diverse and international BioScience team, where you can learn and grow and have the opportunity to play a key role in the discovery and development of future medicines that make a difference in patient lives.
• Good salary and benefits including 8% holiday allowance, 25 days holiday (full time basis). Collective pension with fixed percentage own contribution, bonus scheme. As well-being of our colleagues is important to us, we offer Fisc-free arrangements for discounts on sport memberships, bicycle purchase, etc.

For expat candidates who are already living in Europe we offer
•    a relocation package (including support for the application to the tax authorities for the 30% tax ruling).
•    an expat program, including a Dutch language course and the opportunity to learn more about the Dutch culture.

Acerta Pharma
At our international headquarters in Oss, the Netherlands, we are working to develop new treatment options for patients with specific types of blood cancer. Together with our colleagues of AstraZeneca in US, Canada and UK we are committed to innovative drug discovery and development, especially in the field of haematological oncology.
Acerta has received approval from both the US (FDA) and the European Regulator (EMA) for its small molecule BTK inhibitor for treatment of patients with chronic lymphocytic leukaemia (CLL). In addition, AstraZeneca and Acerta Pharma are collaborating on a large number of other innovative medicines to treat haematological malignant diseases.

How to apply:
We would like to receive your resume (in English) clearly stating your publications. For this, go to the apply button at the bottom of this vacancy. You can upload your CV and cover letter at the bottom of the second page.

If you have any questions about this vacancy, our Recruitment team (Karin Raadschelders, Caroline van Oppen) can be reached via or on +31(0)85 - 047 0244.

Acquisition by recruitment and selection agencies is not appreciated.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Blijf op de hoogte van de laatste farma vacatures


Blijf op de hoogte van de laatste farma vacatures