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(Senior) Operational Excellence Manager

Utrecht, Netherlands

At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

The Role

As operational excellence manager you will drive the execution of operational excellence (OpEx) projects within the Discovery departments of Genmab. You will be responsible for leading OpEx projects aimed at optimizing our line processes, enhancing efficiency, and achieving operational excellence across various functional teams and departments. Within this role you will also coach and support employees in their training and projects. Expertise in process improvement methodologies, change management, project management and leadership are essential for driving continuous improvement and delivering measurable results. This role reports to the director operational excellence.


  • In close collaboration with the department head and team leads, execute and monitor identified OpEx projects within the departments, in the spirit of continuous improvement, focusing on step wise incremental change.

  • Support department heads in their ambition of continuous improvement of their processes and a corresponding culture.

  • Support and coach employees (incl. line management) in training at any lean / 6 sigma belt level.

  • Instill a culture of continuous improvement withing Genmab by supporting projects and personal initiatives within the departments.

  • Support the design and creation of a Genmab specific lean / 6 sigma toolbox and OpEx approach for today and the future.

  • Together with line management develop project specific and department specific KPI’s and stimulate data driven decision-making. Help in statistical analysis.

  • Support in the execution of analysis and data gathering across the complete value chain, for example value chain mapping, SIPOC and other process mapping.


  • A bachelor’s and/or master’s degree within for e.g., Business Administration or Organizational Science.

  • 8+ years of (pharma) manufacturing and/or R&D related experience.

  • 3 to 5 years hands on experience in leading the execution of operations excellence / continuous improvement projects with a proven track record of sustainable results.

  • Strong knowledge of lean / 6 Sigma methodology and tools. Knowledge and/or experience with other process improvement frameworks is a plus. E.g.: A3, process mapping, stakeholder mapping, data gathering and analysis.

  • Certified as Lean / 6 sigma green belt is a must.

  • Black belt or PMP certification is a plus.

  • Excellent communication, presentation, and stakeholder management abilities.

  • Proven project team management skills, with the ability to inspire and motivate team-members and line management.

  • Change management expertise, including experience in driving cultural transformation within departments and overcoming resistance.

  • Ability to work under tight deadlines and be able to work collaboratively in a fast-paced, matrix organization.

  • You have excellent communication skills in English.

About You

  • You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
  • You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
  • You are a generous collaborator who can work in teams with diverse backgrounds
  • You are determined to do and be your best and take pride in enabling the best work of others on the team
  • You are not afraid to grapple with the unknown and be innovative
  • You have experience working in a fast-growing, dynamic company (or a strong desire to)
  • You work hard and are not afraid to have a little fun while you do so


Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Founded in 1999 in Copenhagen, Denmark, Genmab is an innovative biotech company that has become a leader in antibody biology and innovation. Our product pipeline and next-generation antibody technologies are the result of our strong company culture, a deep passion for innovation, and desire to transform cancer treatment and serious diseases.

When you work with us, you’ll be part of a warm, fun, dynamic community, and team up with some of the best, most authentic individuals in locations around the world, who care deeply and share in a relentless drive to innovate and create transformational medicines. People who are candid, impact-driven, and a little unconventional; who seek out and embrace the opportunity to build new and bold futures within a rapidly growing and innovative biotech company; who bring their full selves to work and show up for each other - rolling up their sleeves to get the job done. This translates into a place where you can be authentically you; are empowered to innovate, build solutions, and execute; feel cared for and supported in growth; and are a critical part of changing the lives of patients around the world through transformative cancer treatment.

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website .

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website .

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.

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