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Senior Research Associate Bioconjugation

Oss, Netherlands
Netherlands, Oss

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Synaffix – A Lonza company is a Dutch biotechnology company focused on the advancement of our technology platform for best-in-class antibody-drug conjugates (ADCs). As a leading innovator in the field, our vision is to become world-wide the most prevalent ADC technology for pharma and biotech companies and to realize our ambition – Connect to Cure.

As a result of the increasing number of external ADC collaborations, we are currently looking for a skilled and enthusiastic Research Associate Bioconjugation. You will operate in a team that supports the preparation of ADCs for external collaborations with biotech/pharma companies with key tasks including; setting up experiments, running reactions and purifying intermediates and final products and interpretation of results. In addition you will characterize the produced ADCs with various analytical tools.

Key responsibilities:

  • Execution of experiments following established protocols (including but not limited to performing remodeling and bioconjugation experiments, product purification, product fill-finish and product analysis)
  • Processing, analyzing & documenting of results in ELN
  • Take assigned responsibilities in designated tasks & projects (such as setting-up shipments and performing process optimization)
  • Preparation of production reports and product certificates
  • Supervise other team members with day-to-day execution of the work
  • Work as a team player and work with a high degree of flexibility
  • Provide general support to lab operations
  • Adhere to company policies and quality & safety standards
  • Perform other duties as assigned.

Key requirements:

  • MSc in the field of bioconjugation chemistry or closely related would not be suitable for Phd Candidates
  • An ideal candidate has > 3 years of relevant experience in the field of bioconjugates
  • Experience with various protein purification and analysis techniques including SEC, IEX, affinity chromatography (protein A/L, Ni-NTA), SDS-PAGE, RP-HPLC and MS
  • Experience with handling antibodies, including modification, purification and analysis
  • Hands-on experienced with various bioconjugation chemistry techniques
  • Strong commitment to laboratory work and project delivery
  • Attention to detail and accuracy
  • Strong team-player

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Reference: R59674

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