Intern - (Physical) Chemistry - PATS

Job Description

Are you looking for an internship where you are free to take initiative? Would you like to experience working in one of the biggest multinationals in the pharmaceutical industry? We are looking for a 4th year bachelor (HBO) or master student of (physical) chemistry who is searching for a challenging internship in our innovative company?

Your internship project

To assure the continuity of the supply of all raw materials for a protein crystalline drug product the seed crystals must be replaced by an alternative source. Our drug product manufacturing uses seed crystals to control the crystallization of the API.

As an intern you are responsible to optimize an alternative manufacturing method for the crystalline seeds:

Identify the critical process parameters and corresponding set-points to control the particle size and crystallinity of the protein seed crystals Prepare the final protein drug product at lab scale to compare the effectiveness of your alternative protein crystal seeds in controlling the crystallization of the final protein crystalline drug product

The commercial manufacturing process of the drug product is downscaled to 0.7 L using a Mettler Toledo Optimax labreactor. This reactor set-up is also evaluated as a representative model to simulate the commercial aseptic prepartion of the protein drug product.

Your responsibilities

• Perform the lab scale experiments to screen for the critical process parameters and optimize the set-points of the critical process parameters for manufacturing of the alternative protein seed crystals.

• Prepare the final protein drug product at lab scale to evaluate the effectiveness of your alternative seeds against no seeding and seeding with the current source of protein seed crystals.

• Analyse the resulting material with a.o. laser diffraction, optical microscopy, crystallinity and other techniques

• Evaluate the results and suggest adjustments

• Providing a fresh perspective within the department: your opinion matters.

The above-mentioned responsibilities are an indication of what you will be doing after proper onboarding and initial learning and development. This provides you with the opportunity to learn and hereafter perform tasks independently. In consultation with your supervisor, you could take on additional tasks and responsibilities.

Who are you?

• A 4th year bachelor (HBO) or master student in (physical) chemistry

• You are familiar with crystallization and/or chemical process development

• You are enthusiastic about crystallization of APIs and/or proteins in the pharmaceutical industry

• You are searching for an internship where you have the freedom to take initiative

• You are fluent in English

• You are available for a period of 6 – 9 months for 5 days a week.

What we offer:

Being an intern at our company means you will work together with a team on healthcare in an international environment. As a student, you will get the opportunity to develop yourself. In addition, we offer:

• The possibility to gain experience within the pharmaceutical industry

• The chance to show your potential

• A challenging and dynamic work environment with lots of space to develop yourself

• Professional guidance by an experienced specialist

• A placement fee of € 500,- gross per month (based on a 40-hour week)

Welcome in our team!

Are you enthusiastic about this internship? Apply today and become a part of our team! We are the Global PATS Material Science and Characterization group within our company. We are located in Oss, the Netherlands and are mainly focussed on physicochemical analytics. For this project we are collaborating with the process technology department. The project will be a close collaboration and an internship will be a great chance to gain experiece within the pharmaceutical industry.

Animal Health

Our Animal Health Division is a trusted global leader in veterinary medicine, dedicated to preserving and improving health, well-being, and performance of animals and the people who care for them. We are a global team of professionals working together to make a positive difference in animal care and the world’s food supply and have a deep sense of responsibility towards our customers, consumers, animals, society, and our planet.

Through our commitment to The Science of Healthier Animals®, we offer veterinarians, farmers, pet owners and governments one of the widest ranges of veterinary pharmaceuticals, vaccines and health management solutions and services as well as an extensive suite of digitally connected identification, traceability and monitoring products. We invest in dynamic and comprehensive R&D resources and a modern, global supply chain. We are present in more than 50 countries, while our products are available in some 150 markets.

Who we are …

For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life , Impacting Lives while Inspiring Your Career Growth .

INVENT.

IMPACT.

INSPIRE.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

NLINTERN

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Intern/Co-op (Fixed Term)

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Requisition ID: R268355