Thermo Fisher Scientific zoekt een

Sr Applications Engineer, Product Development Cryo-EM

Eindhoven, Netherlands

Job Description

Sr Application Engineer, cryo-EM

This role is based at our breathtaking site in Eindhoven, The Netherlands and belongs to the Architecture and Validation Department within Research and Development organization for Transmission Electron Microscopes. The immediate team consists of 10 people committed to develop and validate innovative technologies for Cryo-EM and Tomography workflows for our Life Science customers. We are seeking for a highly motivated Engineer who is driven by method/new product development and keen to bring new products to the market.

What will you do? And how will you make an impact?

You will belong to a collaborative team and will focus on the application aspects of product development for Cryo-EM. Cryo-EM workflow is a multi-step process that involves multiple interconnected hardware and software systems to prepare and qualify samples, recording vast amounts of data and images, and processing the collected data into meaningful information, e.g. where the drug is bound to the target. The focus of this position is on understanding the end-user issues, use cases, future needs on sample preparation; then translating them in product requirements and / or functions; then verifying that the solutions are indeed fulfilling the insights. You will work closely with architects, project managers within R&D, and colleagues outside R&D such as business unit, sourcing, operations, and service.

Check out these video’s to get more insight in what it means to work on our sophisticated High-Tech Electron Microscopes. These high-end tools are being developed, market and manufactured in our cleanrooms.

How to make a microscope

Site impression Eindhoven

Key Responsibilities

  • You have a comprehensive view on the Cryo-EM workflow and promote its adoption throughout all layers of R&D Department;
  • author and actively maintain application requirements, specifications and definitions of designs from a workflow perspective:
    • by collaborating with other Application teams and Business Unit to translate the general needs of our customers into solutions,
    • to guide architects and designers on the workflow aspects of the modules, systems and software.
    • by validating that functional and non-functional end-user requirements are fulfilled in the designs of new systems, modules and software functionalities.
  • develop and maintain application roadmaps and stay connected with customers;
  • drive innovation by generating new intellectual property on applications and methods;
  • you write test plans, design test cases, carry out and/or coordinate the execution of these test cases, report issues, and write test reports with recommendations;
  • coordinate and participate in product and process FMEA’s, SRA’s and other risk identification and management practices;
  • participate in the creation of (interactive) user guides, documentation and training materials, and verify the completeness and correctness thereof. You support rollout of new products at launching;
  • guide and support internal and external engineers with solving issues and answering questions in your area of expertise.

Requirements and Competencies

  • Typically requires a University Degree in Physics, Chemistry, Bioengineering or Life Science and 5+ years of industrial experience.
  • Shown hands-on experience with Cryo-EM methods and protocols.
  • Knowledge in at least one of the areas:
    • microfluidics
    • optical detection
    • fluid handling cryo components
    • surface chemistry
    • protein purification and biochemical/biophysical characterization
  • Confirmed experience of creating intellectual property.
  • Experience with statistical engineering tools and ability to handle large amount of data.
  • Mentality of continuous improvement of the Cryo-EM workflow.
  • Strong sense of ownership for work you are doing and responsibilities.
  • Strong communication, eager to learn.

We offer a stimulating work environment in an international organization with ample prospects to grow and develop a long-term career. The role is at the forefront technology with opportunities to interact with customers in academia and pharmaceutical industry.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. Apply today!

Blijf op de hoogte van vacatures zoals deze


Blijf op de hoogte van de laatste vacatures