Intern, Translational Research (Project: Fc-mediated receptor functions in oncology)

Why Genmab

Our internship program provides interns with hands-on experience and relevant projects that directly align with our company’s goals. Additionally, we believe our program provides a valuable opportunity to learn, thrive, and build a strong network. We encourage you to review our website to learn why we’re always looking for smart, purpose-led candidates to play a role in our bold, extra[not]ordinary® future.

The Role
Are you excited about cancer immunology, looking to make a meaningful impact in the field of antibody therapeutics? Do you want to gain exposure to the strategic design of innovative antibody therapeutics? Keep on reading!

We are seeking a highly motivated intern to join one of our Expertise Teams within the Translational Research department. In this lab-based role, you will play an active part in advancing preclinical research for novel antibody therapeutics. Working under the direct supervision of the Expertise Team Lead and a project scientist, you will contribute meaningfully to the development and execution of our preclinical research strategy.

Monoclonal antibodies ( mAbs ) are a major therapeutic modality for many cancer patients, owing to their ability to selectively target tumor-associated antigens. Beyond direct tumor cell binding, mAbs exert immune-mediated effects through their constant Fc regions, which engage immune effector cells and activate the complement system. These Fc-mediated effector functions include antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC).

Responsibilities

You will apply a range of advanced in vitro techniques including cell culture, flow cytometry, live-cell imaging, and functional cellular assays such as ADCC, ADCP, and CDC to investigate these Fc-driven mechanisms in solid tumor models, with a particular focus on understanding how complement influences the modulation and amplification of Fc effector functions.

• With the help of your mentor, you will manage the design, planning, and execution of experiments for assigned research studies .

• Support the research strategy by proposing and designing follow-up experiments informed by emerging data and current literature.

• Stay curious and open to learning new assays, techniques, and analysis methods while approaching challenges with a solutions-driven mindset.

• Document, process, and analyze experimental results promptly. Draw meaningful conclusions, contextualize findings, and present insights to the team.

Requirements

• Currently enrolled in a Bachelor HBO Life Science s or Master’s degree program at a Dutch university in Biomedical Sciences, or a related field.

• Available for a minimum of 6 months (up to 12 months).

• Basic knowledge of immunology, cell biology, and antibody-based therapeutics

• Prior laboratory experience with cell culture and standard cellular techniques is an asset

• Capable of performing data analysis and interpretation, with a strong focus on delivering accurate , reliable, and meaningful research findings

• Ability to work independently and collaboratively within a multidisciplinary team
  
  

Preferred Qualifications, Capabilities, and Skills

• A motivated and curious individual who thrives in collaborative research environments

• Open to feedback and eager to learn new techniques or concepts as needed for the project

• Strong organizational skills and attention to detail.

• Demonstrated ability to manage time effectively and prioritize tasks in a fast-paced research environment

• Familiarity with in vitro assay workflows, including functional assays like ADCC, ADCP, or CDC is a plus (training can be provided) .

• Knowledge of data analysis tools such as Excel, GraphPad Prism, or FlowJo is valued .

• Fluency in English, with the ability to communicate scientific concepts clearly and effectively.
  

General Intern Information

• Internship duration: 6-12 months.

• Start date: September 1st (or later).

• Location: Utrecht, Netherlands

• This is a fulltime onsite internship position.
  

What’s Next?

Help us learn about you by submitting a complete and thoughtful application, which includes your CV and motivation letter. These are a way for us to initially get to know you , so it’s important to complete all relevant questions to ensure we have as much information about you as possible.

Every application matters to us, and we’ll carefully review each submission as quickly as possible to see if your qualifications align with the role. While we’re unable to provide individual updates, rest assured that we’re working diligently to move through the process efficiently.

If you move forward in the process, you’ll receive an email invitation to connect with us and dive deeper into this exciting opportunity. The final stage will bring selected candidates meeting directly with our hiring teams, where you’ll have the chance to showcase your potential. We are committed to keeping you informed and will share decisions with all candidates as soon as we are able. We can't wait to see where this journey takes you!