Merus zoekt een
Protein Scientist (Antibody Engineer)
Utrecht, Netherlands
Are you passionate about antibodies?
Join the innovative Analytical Support team at Merus, where we’re dedicated to the production and characterization of multispecific antibody formats. As a Protein Scientist / Antibody Engineer, you will work within project teams, interacting closely with discovery and preclinical scientists. You’ll play a crucial role in discovering new medicines, working within project teams to create and characterize antibody panels for our groundbreaking assays. This opportunity is for those who are passionate about making a tangible difference in cancer treatments through excellent science and collaborative efforts.
The Role
As a protein scientist / antibody engineer your main task is to ensure that our multispecific antibody candidates meet our stringent developability and manufacturability standards. You will take responsibility for producing and characterizing antibody panels to be tested in our assays, playing a crucial role in the development of advanced therapies.
Your responsibilities within the project teams include the following:
- Design, write and execute experimental studies;
- Cloning and production of large antibody panels;
- Characterization of antibodies in a range of assays including biophysical, affinity, specificity;
- Optimizing antibody sequences for developability and manufacturability;
- Delivering quality results in a timely manner;
- Propagating skills and knowledge to team members;
- Collaboration with external parties.
Your Profile:
We are seeking a Protein Scientist / Antibody Engineer who is not only technically proficient but also thrives in a collaborative environment. The ideal candidate will possess a quality-driven focus and an ability to efficiently manage multiple projects. Your collaborative spirit will be essential as you work within teams that value scientific excellence and strive to push the boundaries of cancer treatment. You will play a key role in a setting that emphasizes both innovation and the real-world impact of your work, aiming to make significant advancements in the field of cancer therapy.
Knowledge and expertise:
- PhD degree in molecular biology or protein chemistry with a minimum of 2 years relevant post-doctoral or industrial experience in protein production and characterization;
- Broad experience in protein chemistry, preferably including antibodies;
- Demonstrated excellence in the eukaryotic expression, purification (FPLC systems) and analysis of recombinant proteins;
- Strong knowledge and technical expertise in protein/antibody characterization including ELISA, FACS, SPR, DSF, SLS/DLS, HPLC (HIC, SEC, Ion Exchange), Mass Spectrometry;
- Experience with protein sequence/structure analysis using computational and homology modelling tools such as BioVia Discovery Studio, Pymol, or Schrödinger is preferred;
As this is a laboratory based position- preference will be given to candidates living in the Netherlands- at a commutable distance to Utrecht Science Park.
Benefits
We offer a once-in-a-lifetime opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll experience a steep learning curve from your very first day in the job. And you’ll get to interact with a great international team of people who love what they do! To top it all, we offer a competitive salary, flexible working hours, an excellent pension scheme, a company bonus and 30 days’ annual leave (based on a full-time position). Most importantly, you’ll have the chance to help us close in on cancer – everything you do matters at Merus.