Research Associate-1
Research Associate
Synaffix is a biotech company with a clinical-stage platform technology that enables best-in-class antibody-drug conjugates (ADCs), bispecific antibodies and other targeted therapeutics under a technology out-licensing business model. Synaffix was fully acquired by Lonza in June 2023. Aimed at enabling innovative medicines for patients in areas of high unmet medical need, Synaffix has forged a growing number of collaborations with top tier biotech and pharma companies by enabling best-in-class therapeutic candidates for their pipelines.
Job description
As a result of the increasing number of external ADC collaborations, we are currently looking for a skilled and enthusiastic Research Associate Bioconjugation. You will operate in a team that supports the preparation of ADCs for external collaborations with biotech/pharma companies with key tasks including; setting up experiments, running reactions and purifying intermediates and final products and interpretation of results. In addition you will characterize the produced ADCs with various analytical tools.
Key tasks
- Execution of experiments following established protocols (including but not limited to performing remodeling and bioconjugation experiments, product purification, product fill-finish and product analysis)
- Processing, analyzing & documenting of results in ELN
- Take assigned responsibilities in designated tasks & projects
- Preparation of production reports and product certificates
- Provide general support to lab operations
Requirements:
- Bsc/Msc in chemical biology, biochemistry, biomedical engineering or related fields
- Professional communication in English both verbally and in writing
- Experience with various protein purification and analysis techniques including SEC, IEX, affinity chromatography (protein A/L, Ni-NTA), SDS-PAGE, RP-HPLC and MS
- Experience with handling antibodies, including modification, purification and analysis.
- Familiarity with various bioconjugation chemistry techniques and preferably hands-on experience
- Strong commitment to laboratory work and project delivery
- Attention to detail and accuracy
- Strong team-player mentality